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Cycloepoxydon

CAT: 0804-HY-N14549Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N14549Size:1 Each
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Description
Cycloepoxydon inhibits the Phorbol 12-myristate 13-acetate (PMA) -induced NF-KB and AP-1 mediated secreted alkaline phosphatase (SEAP) expression with IC50s of 1-2 μg/mL (4.2-8.4 μM) and 3-5 μg/mL (12.6-21 μM), respectively[1].
CAS Number
193481-66-2
UNSPSC
12352005
Target
Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
O[C@@H]1C2=C(CO[C@H]([C@@H]2O)CCC)C([C@]3([H])[C@@]1([H])O3)=O
Molecular Formula
C12H16O5
Molecular Weight
240.25
References & Citations
[1]A Gehrt, et al. Cycloepoxydon, 1-hydroxy-2-hydroxymethyl-3-pent-1-enylbenzene and 1-hydroxy-2-hydroxymethyl-3-pent-1,3-dienylbenzene, new inhibitors of eukaryotic signal transduction. J Antibiot (Tokyo) . 1998 May;51 (5) :455-63.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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