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Diazaquinomycin A

CAT: 0804-HY-N14161Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N14161Size:1 Each
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Description
Diazaquinomycin A (DAQA), a diaza-anthracene antibiotic, is a thymidylate synthase inhibitor. Diazaquinomycin A (DAQA) induces DNA damage, cell cycle arrest, and apoptosis through cleaved-PARP[1].
CAS Number
87614-40-2
UNSPSC
12352005
Target
Apoptosis; Thymidylate Synthase
Related Pathways
Apoptosis
Field of Research
Cancer
Smiles
O=C1NC(C(C(N2)=C3C(CCC)=C(C)C2=O)=O)=C(C(CCC)=C1C)C3=O
Molecular Formula
C20H22N2O4
Molecular Weight
354.40
References & Citations
[1]Michael W Mullowney, et al. Diazaquinomycins E-G, novel diaza-anthracene analogs from a marine-derived Streptomyces sp. Mar Drugs. 2014 Jun 11;12 (6) :3574-86.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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