RegisterLogin

Argyrin A

CAT: 0804-HY-N13904Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-N13904Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Argyrin A, a cyclical peptide, is a potent antitumoral agent. Argyrin A exerts its effects through a potent inhibition of the proteasome. Argyrin A leads to increased endogenous p27kip1 levels by preventing protein turnover[1].
CAS Number
[174423-37-1]
UNSPSC
12352005
Target
Proteasome
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
COC1=C2C(C[C@@H]3NC([C@@H](NC(C4=CSC([C@H](NC(CN(C(C(NC([C@H](NC(CNC3=O)=O)C)=O)=C)=O)C)=O)C)=N4)=O)CC5=CNC6=CC=CC=C56)=O)=CNC2=CC=C1
Molecular Formula
C40H44N10O8S
Molecular Weight
824.90
References & Citations
[1]Nickeleit I, et al. Argyrin a reveals a critical role for the tumor suppressor protein p27 (kip1) in mediating antitumor activities in response to proteasome inhibition. Cancer Cell. 2008 Jul 8;14 (1) :23-35.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

Related Products

CatalogName
HY-P2274-01Argifin
HY-P3461-01Argadin
HY-P2274RArgifin (Standard)
HY-CE01211Argifin-CoA

Alternative Products

CatalogName
TN9118-01Argyrin A
TN9039-01Argyrin B
TN9127-01Argyrin E
TN9008-01Argyrin D
TN9054-01Argyrin F
TN9126-01Argyrin G
TN9025-01Argyrin C
TN9171-01Argyrin H

Popular Products