Bilirubin diglucuronide

• Description:

  Bilirubin diglucuronide is the metabolite of Bilirubin (HY-N0323) . Bilirubin diglucuronide inhibits MRP1/2 mediated ATP-dependent transport of leukotriene C4 (LTC4) in membrane vesicles[1].

• UNSPSC:

  12352005

• Target:

  Drug Metabolite; P-glycoprotein

• Related Pathways:

  Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC(CCC(C(C)=C(N2)/C=C3C(C=C)=C(C(N/3)=O)C)=C2CC4=C(C(C)=C(N4)/C=C5C(C)=C(C(N/5)=O)C=C)CCC(O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)C(O)=O)=O)=O)=O

• Molecular Formula:

  C45H52N4O18

• Molecular Weight:

  936.91

• References & Citations:

  [1]Jedlitschky G, et al., ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2. Biochem J. 1997 Oct 1;327 (Pt 1) (Pt 1) :305-10.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  [17459-92-6]