Bilirubin diglucuronide

CAT: 0804-HY-N11424Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-N11424Size:1 Each
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Description
Bilirubin diglucuronide is the metabolite of Bilirubin (HY-N0323) . Bilirubin diglucuronide inhibits MRP1/2 mediated ATP-dependent transport of leukotriene C4 (LTC4) in membrane vesicles[1].
CAS Number
[17459-92-6]
UNSPSC
12352005
Target
Drug Metabolite; P-glycoprotein
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
OC([C@H]([C@H]([C@@H]([C@H]1O)O)O)O[C@H]1OC(CCC(C(C)=C(N2)/C=C3C(C=C)=C(C(N/3)=O)C)=C2CC4=C(C(C)=C(N4)/C=C5C(C)=C(C(N/5)=O)C=C)CCC(O[C@@H]6O[C@@H]([C@H]([C@@H]([C@H]6O)O)O)C(O)=O)=O)=O)=O
Molecular Formula
C45H52N4O18
Molecular Weight
936.91
References & Citations
[1]Jedlitschky G, et al., ATP-dependent transport of bilirubin glucuronides by the multidrug resistance protein MRP1 and its hepatocyte canalicular isoform MRP2. Biochem J. 1997 Oct 1;327 (Pt 1) (Pt 1) :305-10.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported

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