Bilirubin

Bilirubin

• CAS Number: 635-65-4
• UNSPSC Description: Bilirubin is a yellow breakdown product of heme catabolism[1]. Bilirubin exhibits antioxidant and antimutagenic effects[2].
• Target Antigen: Endogenous Metabolite
• Type: Natural Products
• Related Pathways: Metabolic Enzyme/Protease
• Applications: COVID-19-immunoregulation
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/Bilirubin.html
• Purity: 98.71
• Solubility: 0.1 M HCL : < 1 mg/mL|0.1 M NaOH : < 1 mg/mL (ultrasonic;warming;adjust pH to 9 with H2O;heat to 60°C)|DMSO : 4 mg/mL (ultrasonic;warming;heat to 60°C)
• Smiles: CC(C(N/1)=O)=C(C=C)C1=C\C2=C(C)C(CCC(O)=O)=C(CC3=C(CCC(O)=O)C(C)=C(/C=C4NC(C(C=C)=C\4C)=O)N3)N2
• Molecular Weight: 584.66
• References & Citations: [1]Lu RN, et al. Unconjugated Bilirubin inhibits proteolytic cleavage of von Willebrand factor by ADAMTS13 protease. J Thromb Haemost. 2015 Jun;13(6):1064-72.|[2]Mölzer C, et al. Bilirubin and related tetrapyrroles inhibit food-borne mutagenesis: a mechanism for antigenotoxic action against a model epoxide. J Nat Prod. 2013 Oct 25;76(10):1958-65.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, protect from light)
• Clinical Information: Phase 3