Bilirubin

• Description:

  Bilirubin is a yellow breakdown product of heme catabolism[1]. Bilirubin exhibits antioxidant and antimutagenic effects[2].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/Bilirubin.html

• Purity:

  98.71

• Solubility:

  0.1 M NaOH : 2 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : 5.38 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles:

  CC(C(N/1)=O)=C(C=C)C1=C\C2=C(C)C(CCC(O)=O)=C(CC3=C(CCC(O)=O)C(C)=C(/C=C4NC(C(C=C)=C\4C)=O)N3)N2

• Molecular Formula:

  C33H36N4O6

• Molecular Weight:

  584.66

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Lu RN, et al. Unconjugated Bilirubin inhibits proteolytic cleavage of von Willebrand factor by ADAMTS13 protease. J Thromb Haemost. 2015 Jun;13 (6) :1064-72.|[2]Mölzer C, et al. Bilirubin and related tetrapyrroles inhibit food-borne mutagenesis: a mechanism for antigenotoxic action against a model epoxide. J Nat Prod. 2013 Oct 25;76 (10) :1958-65.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Scientific Category:

  Natural Products

• Clinical Information:

  Phase 3

• Isoform:

  Human Endogenous Metabolite

• CAS Number:

  [635-65-4]