Bilirubin

• UNSPSC Description:

  Bilirubin is a yellow breakdown product of heme catabolism[1]. Bilirubin exhibits antioxidant and antimutagenic effects[2].

• Target Antigen:

  Endogenous Metabolite

• Type:

  Natural Products

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/Bilirubin.html

• Purity:

  98.71

• Solubility:

  0.1 M HCL : < 1 mg/mL|0.1 M NaOH : < 1 mg/mL (ultrasonic;warming;adjust pH to 9 with H2O;heat to 60°C)|DMSO : 4 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  CC(C(N/1)=O)=C(C=C)C1=C\C2=C(C)C(CCC(O)=O)=C(CC3=C(CCC(O)=O)C(C)=C(/C=C4NC(C(C=C)=C\4C)=O)N3)N2

• Molecular Weight:

  584.66

• References & Citations:

  [1]Lu RN, et al. Unconjugated Bilirubin inhibits proteolytic cleavage of von Willebrand factor by ADAMTS13 protease. J Thromb Haemost. 2015 Jun;13(6):1064-72.|[2]Mölzer C, et al. Bilirubin and related tetrapyrroles inhibit food-borne mutagenesis: a mechanism for antigenotoxic action against a model epoxide. J Nat Prod. 2013 Oct 25;76(10):1958-65.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light)

• Clinical Information:

  Phase 3

• CAS Number:

  635-65-4