Yadanzigan

CAT: 0804-HY-N10312-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-N10312-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Yadanzigan (YDZG) is an anti-inflammatory agent and a NLRP3 inhibitor. Yadanzigan specifically inhibits NLRP3 activation via inhibiting NF-κB pathway and Reactive Oxygen Species production. Yadanzigan also moderates LPS -induced acute lung injury (ALI) in mice[1].

CAS Number

76588-87-9

Product Name Alternative

YDZG

UNSPSC

12352005

Target

NF-κB; NOD-like Receptor (NLR) ; Reactive Oxygen Species (ROS)

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Field of Research

Inflammation/Immunology

Solubility

10 mM in DMSO

Smiles

CC1=C[C@H](O[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O2)[C@@H](O)[C@@]3(C)[C@H]1C[C@@H]4[C@]56[C@@H]3[C@@H](O)[C@H](O)[C@@](OC6)(C)[C@]5(O)[C@@H](O)C(O4)=O

Molecular Formula

C26H38O14

Molecular Weight

574.57

References & Citations

[1]Cui Y, et al. Yadanzigan, a quassinoid glucoside, attenuates NLRP3 inflammasome activation to prevent LPS-induced acute lung injury. Authorea Preprints, 2020.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

NLRP3

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