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Tetrazolium Red

CAT: 0804-HY-D0714-01Size: 500 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-D0714-01Size:500 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Tetrazolium Red (2,3,5-Triphenyltetrazolium chloride; TTC) is a not brain-penetrant, colorless, water-soluble dye that is reduced by mitochondrial enzymes to a deep red, water-insoluble compound (formazan) mainly in the mitochondria of living cells. Tetrazolium Red is used to observe the activity of dehydrogenase, and it turns colorless to red when exposed to hydrogen. Tetrazolium Red distinguishes between surviving and infarcted brain tissue after stroke. Tetrazolium Red has been used to stain heart tissue to measure the extent of acute lesions and also used to stain brain tissue to detect the size of the infarcted area. The absorption wavelength of Tetrazolium Red is 570 nm[1][2][3][4].
CAS Number
298-96-4
Product Name Alternative
2,3,5-Triphenyltetrazolium chloride; TPTZ; TTC
UNSPSC
12352200
Hazard Statement
H228, H315, H319
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Cardiovascular Disease
Purity
99.93
Solubility
DMSO : 16.67 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
Smiles
C1(C2=CC=CC=C2)=NN(C3=CC=CC=C3)[N+](C4=CC=CC=C4)=N1.[Cl-]
Molecular Formula
C19H15ClN4
Molecular Weight
334.80
Precautions
H228, H315, H319
References & Citations
[1]Sun YY, et al. Mannitol-facilitated perfusion staining with 2,3,5-triphenyltetrazolium chloride (TTC) for detection of experimental cerebral infarction and biochemical analysis. J Neurosci Methods. 2012 Jan 15;203 (1) :122-9.|[2]Bederson JB, et al. Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. Stroke. 1986 Nov-Dec;17 (6) :1304-8.|[3]Lin YC, et al. Human umbilical mesenchymal stem cells promote recovery after ischemic stroke. Stroke. 2011 Jul;42 (7) :2045-53.|[4]Sylvester PW. Optimization of the tetrazolium dye (MTT) colorimetric assay for cellular growth and viability. Methods Mol Biol. 2011;716:157-68.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported

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