Products for Research Use Only

Rabbit Monoclonal to TRIM29

CAT: 1725-P18310-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P18310-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Plays a crucial role in the regulation of macrophage activation in response to viral or bacterial infections within the respiratory tract. Mechanistically, TRIM29 interacts with IKBKG/NEMO in the lysosome where it induces its 'Lys-48' ubiquitination and subsequent degradation. In turn, the expression of type I interferons and the production of pro-inflammatory cytokines are inhibited. Additionally, induces the 'Lys-48' ubiquitination of STING1 in a similar way, leading to its degradation.
Product Name Alternative
ATDC; TRIM29; ; TRIM29
Swiss Prot
Q14134
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human TRIM29
Clonality
Monoclonal
Applications
WB
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
TRIM29
Bands Size
Calculated MW: 66 kDa ; Observed MW: 68 kDa