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Rabbit Monoclonal to CoREST

CAT: 1725-P18152-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P18152-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Essential component of the BHC complex, a corepressor complex that represses transcription of neuron-specific genes in non-neuronal cells. The BHC complex is recruited at RE1/NRSE sites by REST and acts by deacetylating and demethylating specific sites on histones, thereby acting as a chromatin modifier. In the BHC complex, it serves as a molecular beacon for the recruitment of molecular machinery, including MeCP2 and SUV39H1, that imposes silencing across a chromosomal interval.
Product Name Alternative
COREST; Nr2b2; RCOR; Rcor1; Rxrb; ; REST corepressor 1
Swiss Prot
Q9UKL0
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human REST corepressor 1
Clonality
Monoclonal
Applications
WB, IHC/IHF, IF
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
CoREST
Bands Size
Calculated MW: 53 kDa ; Observed MW: 66 kDa

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