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Nisoxetine (Standard)

CAT: 0804-HY-B1704R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1704R-01Size:5 mg
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Description
Nisoxetine (Standard) is the analytical standard of Nisoxetine. This product is intended for research and analytical applications. Nisoxetine is a potent and selective inhibitor of noradrenaline transporter (NET), with a Kd of 0.76 nM. Nisoxetine is an antidepressant and local anesthetic, it can block voltage-gated sodium channels[1][2][3].
CAS Number
53179-07-0
UNSPSC
12352100
Target
Monoamine Transporter; Reference Standards; Sodium Channel
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Neurological Disease
Smiles
CNCCC(OC1=CC=CC=C1OC)C2=CC=CC=C2
Molecular Formula
C17H21NO2
Molecular Weight
271.35
References & Citations
[1]Béïque JC, et, al. Affinities of venlafaxine and various reuptake inhibitors for the serotonin and norepinephrine transporters. Eur J Pharmacol. 1998 May 15; 349 (1) : 129-32. |[2]Cheetham SC, et, al. [3H]nisoxetine-a radioligand for noradrenaline reuptake sites: correlation with inhibition of [3H]noradrenaline uptake and effect of DSP-4 lesioning and antidepressant treatments. Neuropharmacology. 1996 Jan; 35 (1) : 63-70. |[3]Leung YM, et, al. Nisoxetine blocks sodium currents and elicits spinal anesthesia in rats. Pharmacol Rep. 2013; 65 (2) : 350-7. |[4]Bello NT, et al. High-fat diet-induced alterations in the feeding suppression of low-dose nisoxetine, a selective norepinephrine reuptake inhibitor. J Obes. 2013;2013:457047.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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Alternative Products

CatalogName
BA6777-5Nisoxetine
B6553-5Nisoxetine hydrochloride
A13418-100Nisoxetine hydrochloride 100mg
A13418-50Nisoxetine hydrochloride 50mg
A13418-25Nisoxetine hydrochloride 25mg
A13418-10Nisoxetine hydrochloride 10mg

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