Methantheline (bromide)

• Description:

  Methantheline bromide is a quaternary Ammonium derivate with anticholinergic activity. Methantheline bromide results in a significant greater reduction of axillary sweat production. Methyl bromide can be used in the research of intractable peptic ulcers[1][2].

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H332

• Target:

  Drug Derivative; mAChR

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling; Others

• Field of Research:

  Metabolic Disease; Inflammation/Immunology

• Smiles:

  O=C(OCC[N+](CC)(CC)C)C1C2=C(OC3=C1C=CC=C3)C=CC=C2.[Br-]

• Molecular Formula:

  C21H26BrNO3

• Molecular Weight:

  420.34

• Precautions:

  P261-P264-P270-P271-P304+P340-P330-P501

• References & Citations:

  [1]LIEBOWITZ D, et al. Treatment of intractable peptic ulcer with methantheline (banthine) bromide. J Am Med Assoc. 1952 Oct 18;150 (7) :672-8. English, Undetermined Language. |[2]Müller C, et al. Efficacy and safety of methantheline bromide (Vagantin (®) ) in axillary and palmar hyperhidrosis: results from a multicenter, randomized, placebo-controlled trial. J Eur Acad Dermatol Venereol. 2013 Oct;27 (10) :1278-84.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• CAS Number:

  [53-46-3]