Azaserine (Standard)

• Description:

  Bamethan (hemisulfate) (Standard) is the analytical standard of Bamethan (hemisulfate) . This product is intended for research and analytical applications. Bamethan (DL-Bamethane) hemisulfate is a vasodilator that exhibits significant activity in enhancing blood flow and reducing vascular resistance. Bamethan hemisulfate plays a crucial role in the treatment of cardiovascular conditions by improving oxygen delivery to tissues. Bamethan hemisulfate also aids in the management of hypertension through its relaxing effects on blood vessels.

• Product Name Alternative:

  CI-337 (Standard) ; O-Diazoacetyl-L-serine (Standard) ; P-165 (Standard)

• UNSPSC:

  12352211

• Target:

  Antibiotic; Bacterial; DNA/RNA Synthesis; Reference Standards

• Related Pathways:

  Anti-infection; Cell Cycle/DNA Damage; Others

• Field of Research:

  Cancer; Infection

• Smiles:

  N[C@@H](COC(C=[N+]=[N-])=O)C(O)=O

• Molecular Formula:

  C5H7N3O4

• Molecular Weight:

  173.13

• References & Citations:

  [1]Longnecker DS, Curphey TJ. Adenocarcinoma of the pancreas in azaserine-treated rats. Cancer Res. 1975 Aug;35 (8) :2249-58.|[2]Shigemichi GUNJI, et al. Screening of Antifungal Antibiotics According to Activities Inducing Morphological Abnormalities. Agric. Biol Chem., 47 (9), 2061-2069, 1983.|[3]Williams MV, Tritz GJ. Studies on the modes of action of azaserine inhibition of Escherichia coli. Potentiation of phenylalanine reversal. J Antimicrob Chemother. 1977 Jan;3 (1) :65-77.|[4]Catane R, et al. Azaserine, DON, and azotomycin: three diazo analogs of L-glutamine with clinical antitumor activity. Cancer Treat Rep. 1979 Jun;63 (6) :1033-8. |[5]Lyons SD, et al. Cytotoxic mechanisms of glutamine antagonists in mouse L1210 leukemia. J Biol Chem. 1990 Jul 5;265 (19) :11377-81.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• CAS Number:

  [115-02-6]