Citicoline (Standard)

• Description:

  Citicoline (Cytidine diphosphate-choline) (Standard) is the analytical standard of Citicoline. This product is intended for research and analytical applications. Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline inhibits reactive oxygen species (ROS) and apoptosis. Citicoline can be used for neurological disease and hearing loss study.

• Product Name Alternative:

  Cytidine diphosphate-choline (Standard) ; CDP-Choline (Standard) ; Cytidine 5'-diphosphocholine (Standard)

• UNSPSC:

  12352005

• Target:

  Apoptosis; Caspase; Endogenous Metabolite; Reactive Oxygen Species (ROS) ; Reference Standards

• Related Pathways:

  Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

• Field of Research:

  Cancer; Neurological Disease

• Smiles:

  NC(C=CN1[C@H]2[C@H](O)[C@H](O)[C@@H](COP(OP(OCC[N+](C)(C)C)([O-])=O)(O)=O)O2)=NC1=O

• Molecular Formula:

  C14H26N4O11P2

• Molecular Weight:

  488.32

• References & Citations:

  [1]Davinelli S, et al. Cytoprotective Effects of Citicoline and Homotaurine against Glutamate and High Glucose Neurotoxicity in Primary Cultured Retinal Cells. Oxid Med Cell Longev. 2017;2017:2825703.|[2]Karpova MN, et al. Increase of the seizure threshold in C57BL/6 mice after citicoline administration. Bull Exp Biol Med. 2015 Jan;158 (3) :315-7.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference Standards

• Clinical Information:

  Launched

• Isoform:

  Caspase 3; Caspase 8; Caspase 9

• CAS Number:

  [987-78-0]