RegisterLogin

Ospemifene-d5

CAT: 0804-HY-B0723S2Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-B0723S2Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Ospemifene-d5 (FC-1271a-d5) is deuterium labeled Ospemifene. Ospemifene is a non-estrogen selective estrogen receptor modulator (SERM), with Kis of 380 and 410 nM for estrogen receptor α (ERα) and ERβ, respectively. Ospemifene can be used for the research of vaginal atrophy and breast cancer[1][2].
Product Name Alternative
FC-1271a-d5
UNSPSC
12352005
Target
Estrogen Receptor/ERR; Isotope-Labeled Compounds
Related Pathways
Others; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
ClCC/C(C1=CC=CC=C1)=C(C2=CC=C(OCCO)C=C2)\C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H]
Molecular Formula
C24H18D5ClO2
Molecular Weight
383.92
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Unkila M, et, al. Vaginal effects of ospemifene in the ovariectomized rat preclinical model of menopause. J Steroid Biochem Mol Biol. 2013 Nov;138:107-15.|[3]Bruyniks N, et, al. Systematic indirect comparison of ospemifene versus local estrogens for vulvar and vaginal atrophy. Climacteric. 2017 Jun; 20 (3) : 195-204.|[4]Qiang Qv.et al.Selective estrogenic effects of a novel triphenylethylene compound, FC1271a, on bone, cholesterol level, and reproductive tissues in intact and ovariectomized rats. Endocrinology.Feb;141 (2) :809-20. 25. (2000) .|[5]Tracy L. Taras et al.In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer. The Journal of Steroid Biochemistry and Molecular Biology 77 (4-5) :271-9, (2001) .
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

Related Products

CatalogName
HY-B0723-01Ospemifene
HY-B0723S-01Ospemifene-d4
HY-W717221Medetomidine-d5 (d5-Major)
HY-151913S-01Sebuthylazine-d5 (ethyl-d5)
HY-133171AS-01(S) -Norfluoxetine-d5 (phenyl-d5)
HY-151910S1(±) -Fluoxetine-d5 Oxalate (phenyl-d5)
HY-133171AS1-01(R) -Norfluoxetine-d5 Phthalimide (Phenyl-d5)
HY-W758414Phoxim-d5 (phenyl-d5) (mixture of isomers)
HY-B0940S-01Ethylvanillin-d5
HY-B0575S-01Triamterene-d5

Alternative Products

CatalogName
461661-01Ospemifene
TRC-H950140-2.5MG4-Hydroxy Ospemifene (Ospemifene Impurity)
433981-014’-Hydroxy Ospemifene (Ospemifene Impurity)
447780-01E-Ospemifene
461664-01Ospemifene-d4

Popular Products