Norethindrone-13C2

• Description:

  Norethindrone-13C2 (Norethisterone-13C2) is 13C labeled Norethindrone. Norethindrone is a female progestin approved by FDA for the treatment of endometriosis, uterine bleeding caused by abnormal hormone levels, and secondary amenorrhea.

• Product Name Alternative:

  Norethisterone-13C2

• UNSPSC:

  12352211

• Target:

  Bacterial; Isotope-Labeled Compounds; Progesterone Receptor

• Related Pathways:

  Anti-infection; Others; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Endocrinology; Cancer

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@@]12[C@](CC[C@@]2(O)[13C]#[13CH])([H])[C@@]3([H])[C@]([C@]4([H])C(CC3)=CC(CC4)=O)([H])CC1

• Molecular Formula:

  C18 13C2H26O2

• Molecular Weight:

  300.40

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Muneyyirci-Delale O, et al. Effect of norethindrone acetate in the treatment of symptomatic endometriosis. Int J Fertil Womens Med. 1998 Jan-Feb;43 (1) :24-7.|[3]Kaser DJ, et al. Use of norethindrone acetate alone for postoperative suppression of endometriosis symptoms. J Pediatr Adolesc Gynecol. 2012 Apr;25 (2) :105-8.|[4]Maier WE, et al. Pharmacology and toxicology of ethinyl estradiol and norethindrone acetate in experimental animals. Regul Toxicol Pharmacol. 2001 Aug;34 (1) :53-61.|[5]Cheng DC, et al. Norethindrone acetate inhibition of triglyceride synthesis and release by rat hepatocytes. Atherosclerosis. 1983 Jan;46 (1) :41-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  201741-02-8