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Rabbit Monoclonal to RING2/RING1B/RNF2

CAT: 1725-P18079-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P18079-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Acts as the main E3 ubiquitin ligase on histone H2A of the PRC1 complex, while RING1 may rather act as a modulator of RNF2/RING2 activity (Probable) . Association with the chromosomal DNA is cell-cycle dependent. In resting B- and T-lymphocytes, interaction with AURKB leads to block its activity, thereby maintaining transcription in resting lymphocytes.Also acts as a negative regulator of autophagy by mediating ubiquitination of AMBRA1, leading to its subsequent degradation.
Product Name Alternative
BAP1; DING; BAP-1; HIPI3; RING2; RING1B; ; RING2
Swiss Prot
Q99496
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human RING2
Clonality
Monoclonal
Applications
WB, IHC/IHF, IF, FCM
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
RING2/RING1B/RNF2
Bands Size
38 kDa

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