Elacridar (Standard)

• Description:

  Elacridar (Standard) is the analytical standard of Elacridar. This product is intended for research and analytical applications. Elacridar is an orally active P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP) inhibitor. Elacridar can be used to examine the influence of efflux transporters on agent distribution to brain and the research of cancer[1][2].

• UNSPSC:

  12352100

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  BCRP; P-glycoprotein; Reference Standards

• Related Pathways:

  Membrane Transporter/Ion Channel; Others

• Field of Research:

  Cancer

• Purity:

  97.50

• Smiles:

  O=C1C2=CC=CC(C(NC(C=C3)=CC=C3CCN4CC(C=C(C(OC)=C5)OC)=C5CC4)=O)=C2NC6=C1C=CC=C6OC

• Molecular Formula:

  C34H33N3O5

• Molecular Weight:

  563.64

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Sane R, et al. Brain distribution and bioavailability of elacridar after different routes of administration in the mouse. Drug Metab Dispos. 2012 Aug;40 (8) :1612-9.|[2]Sato H, et al. Elacridar enhances the cytotoxic effects of sunitinib and prevents multidrug resistance in renal carcinoma cells. Eur J Pharmacol. 2015 Jan 5;746:258-66.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, sealed storage, away from light and moisture

• Scientific Category:

  Reference Standards

• CAS Number:

  [143664-11-3]