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Rabbit Monoclonal to NFE2

CAT: 1725-P17973-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1725-P17973-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR) . This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.
Product Name Alternative
Nfe2 ; Nuclear factor; p45 NFE2; ; NFE2
Swiss Prot
Q16621
Host
Rabbit
Reactivity
Human
Immunogen
A synthesized peptide derived from human NFE2
Clonality
Monoclonal
Applications
WB, IHC/IHF, IF, IP
Storage Conditions
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Formulation
Purified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.
Antibody Type
Primary antibody
Protein Name
NFE2
Bands Size
Calculated MW: 41 kDa ; Observed MW: 45 kDa

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