TRO-40303

• Description :

  TRO-40303 is a cell protective compound targeting mitochondrial TSPO. TRO-40303 significantly improves the survival rate of liver cells and reduces cell death by reducing oxidative stress. TRO-40303 is commonly used in the study of hepatitis[1].

• CAS Number :

  [949080-24-4]

• UNSPSC :

  12352211

• Target :

  TSPO

• Related Pathways :

  Neuronal Signaling

• Field of Research :

  Inflammation/Immunology

• Smiles :

  C[C@]([C@]1([H])[C@]2([H])[C@]3([H])CC[C@H]([C@H](C)CCCC(C)C)[C@@]3(C)CC1)(CCCO)/C(CC2)=N/O

• Molecular Formula :

  C26H47NO2

• Molecular Weight :

  405.66

• References & Citations :

  [1]Schaller S, et al. TRO40303, a mitochondrial-targeted cytoprotective compound, provides protection in hepatitis models. Pharmacol Res Perspect. 2015 Jun;3 (3) :e00144.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2