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ML278

CAT: 0804-HY-19616Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-19616Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ML278 is an efficient, low toxicity, and plasma stable SR-BI (IC50 = 6 nM) lipid uptake inhibitor. ML278 enhances HDL binding while inhibiting SR-BI mediated lipid uptake. ML278 can be used for research on metabolic conditions[1].
CAS Number
[1604821-43-3]
UNSPSC
12352005
Target
Scavenger Receptor Class B type I (SR-BI)
Related Pathways
Immunology/Inflammation
Field of Research
Metabolic Disease
Smiles
O=C(NC1=NC(C2=CC3=C(N(C(COC)=O)CC3)C=C2)=CS1)C4=CC(OC)=CC(OC)=C4
Molecular Formula
C23H23N3O5S
Molecular Weight
453.51
References & Citations
[1]Dockendorff C, et al. Indolinyl-Thiazole Based Inhibitors of Scavenger Receptor-BI (SR-BI) -Mediated Lipid Transport. ACS Med Chem Lett. 2015 Feb 2;6 (4) :375-380.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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