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Idrabiotaparinux (sodium)

CAT: 0804-HY-19442ASize: 1 EachDry Ice: NoHazardous: No
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Description
Idrabiotaparinux sodium is a derivative of Idraparinux synthesized with biotin. Idraparinux is a polymethylated synthetic pentasaccharide known to interact with the antithrombin III and act as anticoagulant[1][2].
CAS Number
405159-59-3
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Thrombin
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Solubility
10 mM in DMSO
Smiles
O=S(O[C@H]([C@H]([C@@H](O[C@@]1([H])[C@@H]([C@H]([C@H](O[C@@]2([H])[C@@H]([C@H]([C@@H](OC)O[C@@H]2COS(=O)(O[Na])=O)OS(=O)(O[Na])=O)OS(=O)(O[Na])=O)O[C@H]1C(O[Na])=O)OC)OC)O[C@@H]3COS(=O)(O[Na])=O)OS(=O)(O[Na])=O)[C@]3([H])O[C@H]4[C@@H]([C@H]([C@@](O[C@@H]5[C@@H]([C@H]([C@H](OC)[C@@H](COS(=O)(O[Na])=O)O5)OC)NC(CCCCCNC(CCCC[C@H]6[C@](N7)([H])[C@](NC7=O)([H])CS6)=O)=O)([H])[C@@H](C(O[Na])=O)O4)OC)OC)(O[Na])=O
Molecular Formula
C53H79N4Na9O51S8
Molecular Weight
2051.62
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Harenberg J. Development of idraparinux and idrabiotaparinux for anticoagulant therapy. Thromb Haemost. 2009;102 (5) :811-815. |[2]Paty I, Trellu M, Destors JM, Cortez P, Boëlle E, Sanderink G. Reversibility of the anti-FXa activity of idrabiotaparinux (biotinylated idraparinux) by intravenous avidin infusion. J Thromb Haemost. 2010;8 (4) :722-729.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported