SS-750

• Description:

  SS-750 is an orally active Triazole derivative and antifungal agent. SS-750 binds to fungal cytochrome P450. SS-750 shows antifungal activities against Candida species and C. neoformans strains tested. SS750 shows MIC90 values of 0.25, 1, and 2 μg/mL against Candida parapsilosis, C. krusei, and C. glabrata, respectively. SS-750 improves systemic and pulmonary candidiasis caused by C. albicans[1].

• UNSPSC:

  12352005

• Target:

  Cytochrome P450; Fungal

• Related Pathways:

  Anti-infection; Metabolic Enzyme/Protease

• Field of Research:

  Infection

• Smiles:

  CCS(C(F)(F)[C@@](O)(C1=C(C=C(C=C1)F)F)CN2C=NC=N2)(=O)=O

• Molecular Formula:

  C13H13F4N3O3S

• Molecular Weight:

  367.32

• References & Citations:

  [1]Matsumoto M, et al. Strong antifungal activity of SS750, a new triazole derivative, is based on its selective binding affinity to cytochrome P450 of fungi. Antimicrob Agents Chemother. 2002 Feb;46 (2) :308-14.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [229153-17-7]