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FR-158999

CAT: 0804-HY-19275Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19275Size:1 Each
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Description
FR-158999 is a potent orally active fibrinogen inhibitor. FR-158999 exhibits potent anti-platelet activities with a pIC50 of 7.50. FR-158999 can be used for antithrombotic research[1].
CAS Number
160138-41-0
UNSPSC
12352005
Target
Integrin
Related Pathways
Cytoskeleton
Field of Research
Cardiovascular Disease
Smiles
O=C(O)C[C@H](NC(CCCOC1=CC=C(C(N)=N)C=C1)=O)C(N[C@H](C(N2CCS(CC2)(=O)=O)=O)C(C)C)=O
Molecular Formula
C24H35N5O8S
Molecular Weight
553.63
References & Citations
[1]Tanaka A, et al. QSAR study of the peptidic fibrinogen inhibitors FK633, FR158999 and related derivatives, using a novel and useful hydrophobic descriptor (logPmw) . Bioorg Med Chem Lett. 1998 Sep 22;8 (18) :2483-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

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