FR-158999

• Description:

  FR-158999 is a potent orally active fibrinogen inhibitor. FR-158999 exhibits potent anti-platelet activities with a pIC50 of 7.50. FR-158999 can be used for antithrombotic research[1].

• UNSPSC:

  12352005

• Target:

  Integrin

• Related Pathways:

  Cytoskeleton

• Field of Research:

  Cardiovascular Disease

• Smiles:

  O=C(O)C[C@H](NC(CCCOC1=CC=C(C(N)=N)C=C1)=O)C(N[C@H](C(N2CCS(CC2)(=O)=O)=O)C(C)C)=O

• Molecular Formula:

  C24H35N5O8S

• Molecular Weight:

  553.63

• References & Citations:

  [1]Tanaka A, et al. QSAR study of the peptidic fibrinogen inhibitors FK633, FR158999 and related derivatives, using a novel and useful hydrophobic descriptor (logPmw) . Bioorg Med Chem Lett. 1998 Sep 22;8 (18) :2483-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  Phase 1

• CAS Number:

  [160138-41-0]