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BTS-67582

CAT: 0804-HY-19174Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19174Size:1 Each
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Description
BTS-67582 is an orally active nonsulfonylurea insulinotropic agent and potassium channel blocker. BTS-67582 affects the K+ ATP channel in the islet cell but at a different binding site than the sulfonylureas. BTS-67582 is an antidiabetic agent[1][2].
CAS Number
161748-40-9
UNSPSC
12352005
Target
Potassium Channel
Related Pathways
Membrane Transporter/Ion Channel
Field of Research
Inflammation/Immunology; Metabolic Disease
Smiles
N=C(NC1=CC=CC=C1N2CCOCC2)N(C)C.O=C(O)/C=C/C(O)=O
Molecular Formula
C17H24N4O5
Molecular Weight
364.40
References & Citations
[1]Skillman CA, Raskin P. A double-masked placebo-controlled trial assessing effects of various doses of BTS 67,582, a novel insulinotropic agent, on fasting hyperglycemia in NIDDM patients. Diabetes Care. 1997 Apr;20 (4) :591-6. 7,582, a Novel Insulinotropic Agent, on Fasting Hyperglycemia in NIDDM Patients|[2]Louchami K, et al. Effect of 1,1-dimethyl-2-[2-morpholinophenyl]guanidine fumarate on pancreatic islet function. Eur J Pharmacol. 1998 Jul 10;352 (2-3) :289-97.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2

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