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JO-1870 (hydrochloride)

CAT: 0804-HY-19122Size: 1 EachDry Ice: NoHazardous: No
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Description
JO-1870 hydrochloride is a selective opioid receptor agonist. JO-1870 hydrochloride exerts bladder relaxation via activation of opioid receptors. JO-1870 hydrochloride is promising for research of urinary incontinence[1].
CAS Number
141034-43-7
UNSPSC
12352005
Target
Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Metabolic Disease
Smiles
CCC(C1=CC=C(Cl)C=C1)(N(C)C)C/C=C/C2=CC=CC=C2.Cl
Molecular Formula
C20H25Cl2N
Molecular Weight
350.33
References & Citations
[1]Soulard C, et al. Pharmacological evaluation of JO 1870: relation to the potential treatment of urinary bladder incontinence. J Pharmacol Exp Ther. 1992 Mar;260 (3) :1152-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

1-(4-Chlorophenyl)-N,N-dimethyl-1-ethyl-(4-phenyl)but-3-en-1-ylamine

may have potential use in the treatment of urinary incontinence; structure given in first source

CAS Number141034-43-7
PubChem CID6439430
IUPAC Name(E)-3-(4-chlorophenyl)-N,N-dimethyl-6-phenylhex-5-en-3-amine;hydrochloride
Molecular FormulaC20H25Cl2N
Molecular Weight350.3
Topological Polar Surface Area3.2
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count6
Heavy Atom Count23
Formal Charge0
Complexity338
SMILES
CCC(C/C=C/C1=CC=CC=C1)(C2=CC=C(C=C2)Cl)N(C)C.Cl
InChI
InChI=1S/C20H24ClN.ClH/c1-4-20(22(2)3,18-12-14-19(21)15-13-18)16-8-11-17-9-6-5-7-10-17;/h5-15H,4,16H2,1-3H3;1H/b11-8+;
InChIKey
MGMLEOAQYQETSX-YGCVIUNWSA-N
Chemical Structure
2D Structure
2D structure of 1-(4-Chlorophenyl)-N,N-dimethyl-1-ethyl-(4-phenyl)but-3-en-1-ylamine
CAS: 141034-43-7
CID: 6439430
Formula: C20H25Cl2N
MW: 350.3
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight350.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count6
Exact Mass349.1364052
Monoisotopic Mass349.1364052
Topological Polar Surface Area3.2 Ų
Heavy Atom Count23
Formal Charge0
Complexity338
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

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