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Trimethidinium (methosulfate)

CAT: 0804-HY-180382Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-180382Size:1 Each
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Description
Trimethidinium methosulfate is an orally active ganglionic blocker with central antihypertensive activity. Trimethidinium methosulfate inhibits the conduction of sympathetic ganglia and reduces vascular contraction. Trimethidinium methosulfate acts on the cerebrovascular motor center and lowers peripheral vascular resistance. Trimethidinium methosulfate has cholinergic nerve inhibitory side effects, but they are relatively mild. Trimethidinium methosulfate can be used in hypertension research[1][2].
CAS Number
14149-43-0
UNSPSC
12352005
Target
Cholinesterase (ChE)
Related Pathways
Neuronal Signaling
Field of Research
Cardiovascular Disease
Smiles
O=S([O-])(OC)=O.CC1(C2CCC1(C[N+](CCC[N+](C)(C)C)(C2)C)C)C.O=S([O-])(OC)=O
Molecular Formula
C19H42N2O8S2
Molecular Weight
490.68
References & Citations
[1]PELNER L, WALDMAN S. Trimethidinium methosulfate in the treatment of moderate and severe hypertension. J Am Geriatr Soc. 1960 Mar;8:168-76. |[2]BORHANI NO. Use of trimethidinium methosulfate (a new ganglionic blocking agent) in the treatment of hypertension. Ann Intern Med. 1959 Nov;51:983-92.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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