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ASGPR ligand-2

CAT: 0804-HY-179737Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179737Size:1 Each
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Description
ASGPR ligand-2 (Compound 366) is an asialoglycoprotein receptor (ASGPR) binder. ASGPR ligand-2 can be coupled with recognition elements of target proteins (such as antibodies or antigen-binding fragments), and through the endocytosis mediated by ASGPR, the target protein is delivered to the lysosomes of liver cells, promoting the degradation of the target protein. ASGPR ligand-2 can be used for the research of metabolic disease[1].
CAS Number
3062599-51-0
UNSPSC
12352005
Target
LYTACs
Related Pathways
PROTAC
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
[N-]=[N+]=NCCOCCOCCOCC(NCCOCCC(NCCOCCOCCO[C@H]1[C@@H]([C@H]([C@H]([C@H](O1)CO)O)O)NC(C)=O)=O)=O
Molecular Formula
C27H50N6O14
Molecular Weight
682.72
References & Citations
[1]Wieslaw Kazmierski, et al. Asgpr binders and compositions and methods thereof. WO2024229005A2. 2025-10-30
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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Alternative Products

CatalogName
GTR19217828-01ASGPR ligand-1
A8510-05ASGR2 (Asialoglycoprotein Receptor 2, ASGP-R 2, ASGPR 2, C-type Lectin Domain Family 4 Member H2, Hepatic Lectin H2, HL-2, CLEC4H2)
A8510-05-HRPASGR2 (Asialoglycoprotein Receptor 2, ASGP-R 2, ASGPR 2, C-type Lectin Domain Family 4 Member H2, Hepatic Lectin H2, HL-2, CLEC4H2) (HRP)
A8510-05-PEASGR2 (Asialoglycoprotein Receptor 2, ASGP-R 2, ASGPR 2, C-type Lectin Domain Family 4 Member H2, Hepatic Lectin H2, HL-2, CLEC4H2) (PE)
MBS6140325-01ASGR2 (Asialoglycoprotein Receptor 2, ASGP-R 2, ASGPR 2, C-type Lectin Domain Family 4 Member H2, Hepatic Lectin H2, HL-2, CLEC4H2) (Biotin)
A8510-05-FITCASGR2 (Asialoglycoprotein Receptor 2, ASGP-R 2, ASGPR 2, C-type Lectin Domain Family 4 Member H2, Hepatic Lectin H2, HL-2, CLEC4H2) (FITC)
A8510-05-APCASGR2 (Asialoglycoprotein Receptor 2, ASGP-R 2, ASGPR 2, C-type Lectin Domain Family 4 Member H2, Hepatic Lectin H2, HL-2, CLEC4H2) (APC)
MBS6129719-01ASGR2 (Asialoglycoprotein Receptor 2, ASGP-R 2, ASGPR 2, C-type Lectin Domain Family 4 Member H2, Hepatic Lectin H2, HL-2, CLEC4H2) (AP)
MBS6135022-01ASGR2 (Asialoglycoprotein Receptor 2, ASGP-R 2, ASGPR 2, C-type Lectin Domain Family 4 Member H2, Hepatic Lectin H2, HL-2, CLEC4H2) APC
A8510-05-APASGR2 (Asialoglycoprotein Receptor 2, ASGP-R 2, ASGPR 2, C-type Lectin Domain Family 4 Member H2, Hepatic Lectin H2, HL-2, CLEC4H2) (AP) discontinued

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