DAM-001

CAT: 0804-HY-179714Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-179714Size:1 Each
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Description
DAM-001 (Z236004662) is a potent, non-competitive allosteric inhibitor for human dopamine transporter (hDAT) with an IC50 of 24.70 μM and 1.026 μM in the absence and presence of orthosteric inhibitor Nomifensine (HY-B1110) [1].
CAS Number
[1090396-31-8]
Product Name Alternative
Z236004662
UNSPSC
12352005
Target
Dopamine Transporter
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(C1CCCC1)N(CCC2)CC2C3=NC4=CC=CC=C4N3
Molecular Formula
C18H23N3O
Molecular Weight
297.39
References & Citations
[1]Ye X, et al. Discovery of a new allosteric inhibitor for human dopamine transporter by physics-based modeling and experimental validation. Eur J Med Chem. 2026 Feb 5;303:118403.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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