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Antiviral agent 74

CAT: 0804-HY-179638Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179638Size:1 Each
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Description
Antiviral agent 74 is an antiviral agent consisting of Cidofovir prodrug and lipid chain. Antiviral agent 74 can inhibit the activity of viral DNA polymerase by transforming into Cidofovir.Antiviral agent 74 demonstrates potent antiviral activity against vacciniavirus (VACV) (EC50 = 0.156 μM) comparable to Brincidofovir (HY-14532). Antiviral agent 74 shows superior potency against monkeypox virus (MPXV) with an EC50 vales of 0.202 μM. Antiviral agent 74 can be used for the research of virus infection[1].
CAS Number
3059641-72-1
UNSPSC
12352005
Target
DNA/RNA Synthesis; Orthopoxvirus
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
OP(OCCS(CCCCCCCCCCCCCCCCCC)(=O)=O)(CO[C@H](CO)CN1C=CC(N)=NC1=O)=O
Molecular Formula
C28H54N3O8PS
Molecular Weight
623.78
References & Citations
[1]Wang B, et al. Lipid-Optimized Sulfone-Bridged Cidofovir Prodrugs as Potent Antivirals Against Orthopoxviruses. J Med Chem. 2025;68 (22) :23867-23885.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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