Antiviral agent 9

• Target :

  Others|||HIV Protease

• Related Pathways :

  Others|||Microbiology/Virology|||Proteases/Proteasome

• Bioactivity :

  Antiviral agent 9 exhibits potent efficacy against HIV-1 with an EC50 value of 0.006 nM, indicating extremely low concentrations are sufficient to inhibit the virus. Additionally, it demonstrates a selectivity index (SI) nearly 300 times higher than that of tenofovir alafenamide fumarate (TAF), outlining its superior selectivity and potential safety profile.

• Smiles :

  C[C@H](CN1C=NC2=C(N=CN=C21)N)OCP(=O)(N[C@@H](C)C(=O)OC(C)C)OC3=CC=C(C=C3)C[C@@H](C(=O)CC4CCCC4)NC(=O)OCC5=CC=CC=C5

• Molecular Formula :

  C38H50N7O8P

• Molecular Weight :

  763.82

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C