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GSK4394835A

CAT: 0804-HY-179595Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179595Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSK4394835A is a reversible covalent inhibitor of PDE3B with a pIC50 of 6.2. GSK4394835A can be used for cardiovascular disease research[1].
CAS Number
3032458-06-0
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
O=C(C1=CC(OC)=C2C=CC(OC)=CC2=N1)NC3=CC(C(N(CC4=CC=CC=C4)C)=O)=CC(B(O)O)=C3
Molecular Formula
C27H26BN3O6
Molecular Weight
499.32
References & Citations
[1]Samuel A. Eaton, et al. Covalent Binding of Boronic Acid-Based Inhibitor GSK4394835A to Phosphodiesterase 3B, a Drug Target for Cardiovascular Disease. bioRxiv. October 22, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PDE3

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CatalogName
GTR19274243-01GSK4394835A

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