BCECF Acetoxymethyl ester

CAT: 0804-HY-179547Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-179547Size:1 Each
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Description
BCECF Acetoxymethyl ester is a fluorescent indicator for estimating intracellular pH. BCECF Acetoxymethyl ester is modified by intracellular esterases to produce BCECF. Intracellular pH measurements are made by ratio imaging, which involves determining the pH-dependent ratio of emission intensity (detected at 535 nm) when the dye is excited at 490 nm vs. the emission intensity when excited at 440 nm[1][2][3].
CAS Number
[1119449-23-8]
UNSPSC
12352005
Target
Fluorescent Dye
Related Pathways
Others
Field of Research
Others
Smiles
O=C(C1=CC=C2C(C(OC23C4=C(OC5=C3C=C(CCC(OCOC(C)=O)=O)C(OCOC=O)=C5)C=C(OCOC(C)=O)C(CCC(OCOC(C)=O)=O)=C4)=O)=C1)OCOC(C)=O
Molecular Formula
C41H38O21
Molecular Weight
866.73
References & Citations
[1]Bachmeier CJ, et al. Drug efflux transport properties of 2',7'-bis (2-carboxyethyl) -5 (6) -carboxyfluorescein acetoxymethyl ester (BCECF-AM) and its fluorescent free acid, BCECF. J Pharm Sci. 2004 Apr;93 (4) :932-42.|[2]Dive C, et al. Polar fluorescein derivatives as improved substrate probes for flow cytoenzymological assay of cellular esterases. Mol Cell Probes. 1988 Jun;2 (2) :131-45.|[3]O'Connor N, et al. Ratio imaging: practical considerations for measuring intracellular Ca2+ and pH in living cells. Methods Cell Biol. 2007;81:415-33.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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CatalogName
MBS8579940-01BCECF, AM [2', 7'-bis-(2-carboxyethyl)-5-(and-6)-carboxyfluorescein, acetoxymethyl ester]
E37F21202BCECF,-AM--[2',7'-bis-(2-carboxyethyl)-5-(and-6)-carboxyfluorescein,-acetoxymethyl-ester]
E37F21202-1 mgBCECF, AM [2',7'-bis- (2-carboxyethyl) -5- (and-6) -carboxyfluorescein, acetoxymethyl ester]
E37F21202-1-mgBCECF, AM [2',7'-bis-(2-carboxyethyl)-5-(and-6)-carboxyfluorescein, acetoxymethyl ester]
E37F21202-100 μLBCECF, AM [2',7'-bis- (2-carboxyethyl) -5- (and-6) -carboxyfluorescein, acetoxymethyl ester] *5mM solution in anhydrous DMSO*
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