HBV-IN-54

CAT: 0804-HY-179393Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-179393Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

HBV-IN-54 is a selective and orally active HBV inhibitor. HBV-IN-54 exhibits anti-HBV activity in both HepAD38 cells (EC50 = 0.020 μM, CC50 > 100 μM) and HLCZ01 cells (EC50 = 0.024 μM, CC50 > 100 μM) . HBV-IN-54 inhibits viral replication in vivo. HBV-IN-54 displays favorable physicochemical properties and high plasma stability. HBV-IN-54 can be used for research on Hepatitis B (HBV) [1].

UNSPSC

12352005

Target

HBV

Related Pathways

Anti-infection

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CC1=C(C=C(C(F)=C1)NC(N2CCN(CC2)CCO)=S)C(NC3=CC(C)=C(C=C3)F)=O

Molecular Formula

C22H26F2N4O2S

Molecular Weight

448.53

References & Citations

[1]Liang M, et al. Multisite Occupancy and Multidimensional Optimization: Design and Evaluation of Piperazine-Thioureidobenzamide Derivatives as Potent HBV Capsid Assembly Modulators. J Med Chem. 2025 Nov 27;68 (22) :24358-24380.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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