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PLTP-IN-1

CAT: 0804-HY-179364Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179364Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PLTP-IN-1 (cpd B) is a selective phospholipid transfer protein (PLTP) inhibitor with an IC50 of 1.6 μM. PLTP-IN-1 can block the phospholipid transfer mediated by PLTP and reduce the secretion of apolipoprotein B. PLTP-IN-1 has no effect on the level of triglycerides. PLTP-IN-1 can be used for the research of metabolic disease, such as hyperlipidemia[1].
CAS Number
1224565-08-5
UNSPSC
12352005
Target
Apolipoprotein
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Smiles
FC1=CC=CC(CN2C3C4=C(C2CN(C3)CC5=CC=C(C(OCC)=C5)OC)C=CC=C4)=C1
Molecular Formula
C27H29FN2O2
Molecular Weight
432.53
References & Citations
[1]Luo Y, et al. Pharmacologic inhibition of phospholipid transfer protein activity reduces apolipoprotein-B secretion from hepatocytes. J Pharmacol Exp Ther. 2010 Mar;332 (3) :1100-6.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ApoB

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