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Proteasome-IN-8

CAT: 0804-HY-179273Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179273Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Proteasome-IN-1 (Compound 130) is a proteasome inhibitor. Proteasome-IN-1 exhibits antiparasitic activity against P. faciparum 3D7[1].
CAS Number
3097658-48-2
UNSPSC
12352005
Target
Parasite; Proteasome
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
O=C([C@@H]1CN(C(COC[C@H](N)C2=CC=CC=C2)=O)CCC1)NCC3=NC(C4=CC=C(C(F)(F)F)C=C4)=CS3
Molecular Formula
C27H29F3N4O3S
Molecular Weight
546.60
References & Citations
[1]Gahalawat S, et al. Optimization of Species-Selective Reversible Proteasome Inhibitors for the Treatment of Malaria. J Med Chem. 2025 Nov 13;68 (21) :23485-23520.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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