LAG-3 PROTAC-1

CAT: 0804-HY-179060Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-179060Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
LAG-3 PROTAC-1 is a potent LAG-3 PROTAC degrader with a DC50 of 0.27 μM. LAG-3 PROTAC-1 can be used in cancer immunology research (pink: LAG-3 ligand (HY-179061) ; blue: CRBN ligand (HY-10984) ; black: linker; CRBN ligand + linker (HY-131888A) ) [1].
UNSPSC
12352005
Target
LAG-3; PROTACs
Related Pathways
Immunology/Inflammation; PROTAC
Field of Research
Cancer
Smiles
O=C(NCCCCNC1=CC=CC(C(N2C3CCC(NC3=O)=O)=O)=C1C2=O)[C@H]([C@@H](C4=CC=CC=C4)C5)CN5CC6=CC=CC=N6
Molecular Formula
C34H36N6O5
Molecular Weight
608.69
References & Citations
[1]Vázquez NG, et al. Design and validation of the first-in-class PROTACs for targeted degradation of the immune checkpoint LAG-3. Bioorg Med Chem Lett. 2025 Oct 4;130:130428.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon

Related Products

CatalogName
HY-176814LAG-3-IN-1
HY-179061LAG-3 degrader 1
HY-162811LAG-3 biner 1
HY-178320LAG-3-IN-2
HY-149845-01PROTAC GSK-3β Degrader-1
HY-114323-01PROTAC FLT-3 degrader 1
HY-179075PROTAC BCL6/IKZF1/3 Degrader-1
HY-179077PROTAC BTK/IKZF1/3 Degrader-1
HY-176813LAG-3 Hit II
HY-P73844LAG-3, Mouse (HEK293)

Alternative Products

CatalogName
MF-0119385-01LAG-3-IN-1
MF-0142389-01LAG-3 biner 1
MBS3843142-01PROTAC FLT-3 degrader 1
chm-018LAG-1
MF-0116895-01PROTAC GSK-3? Degrader-1
A18682-1PROTAC FLT-3 degrader 1 1mg
A18682-10PROTAC FLT-3 degrader 1 10mg
PT_73233-01LAG-1 (CCL4L1) Human Recombinant (LAG-1 Human)
A18682-5PROTAC FLT-3 degrader 1 5mg
C00923Tebotelimab (Anti-LAG-3 & PD-1)

Popular Products