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GSTA4-IN-1

CAT: 0804-HY-179057Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179057Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
GSTA4-IN-1 (Compound 3a) is a potent and competitive inhibitor of glutathione S-transferase A4 (GSTA4), with an IC50 of 3.12 μM and a Ki of 2.38 μM. GSTA4-IN-1 is cytotoxic to colorectal cancer cells. GSTA4-IN-1 can be used for research on colorectal cancer[1].
UNSPSC
12352005
Target
Glutathione S-transferase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C(NC1=CC=CC(F)=C1)NC2=NN=C(CC3=C(C)N(C(C4=CC=C(Cl)C=C4)=O)C5=C3C=C(OC)C=C5)S2
Molecular Formula
C27H21ClFN5O3S
Molecular Weight
550.00
References & Citations
[1]Dişer AS, et al. Synthesis of indomethacin thiadiazole urea derivatives and determination of GSTA4 inhibition and cytotoxic activity against colorectal carcinoma. Bioorg Chem. 2025 Oct 18;166:109118.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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