GSTA4-IN-1

• Description:

  GSTA4-IN-1 (Compound 3a) is a potent and competitive inhibitor of glutathione S-transferase A4 (GSTA4), with an IC50 of 3.12 μM and a Ki of 2.38 μM. GSTA4-IN-1 is cytotoxic to colorectal cancer cells. GSTA4-IN-1 can be used for research on colorectal cancer[1].

• UNSPSC:

  12352005

• Target:

  Glutathione S-transferase

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cancer

• Smiles:

  O=C(NC1=CC=CC(F)=C1)NC2=NN=C(CC3=C(C)N(C(C4=CC=C(Cl)C=C4)=O)C5=C3C=C(OC)C=C5)S2

• Molecular Formula:

  C27H21ClFN5O3S

• Molecular Weight:

  550.00

• References & Citations:

  [1]Dişer AS, et al. Synthesis of indomethacin thiadiazole urea derivatives and determination of GSTA4 inhibition and cytotoxic activity against colorectal carcinoma. Bioorg Chem. 2025 Oct 18;166:109118.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported