Remodelin-C6-COOH

• Description:

  Remodelin-C6-COOH is a synthesized target protein ligand-linker conjugate that can be used for synthesis of NP1192 (HY-178360) . NP1192 is a potent NAT10 PROTAC degrader with anti-tumor activity[1].

• UNSPSC:

  12352005

• Target:

  Target Protein Ligand-Linker Conjugates

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Smiles:

  N#CC1=CC=C(C=C1)C2=CSC(N(/N=C3CCCC/3)CCCCCCC(O)=O)=N2

• Molecular Formula:

  C22H26N4O2S

• Molecular Weight:

  410.53

• References & Citations:

  [1]Ao, K., et al. Targeted NAT10 Degradation by PROTAC NP1192 Suppresses Hypoxia-Adaptive Glycolysis and Reinvigorates CD8+ Effector T-Cell Function for Synergistic Cancer Immunotherapy. ACS Central Science. 2025.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2966791-35-3]