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ER121

CAT: 0804-HY-177989-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-177989-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
ER121 (SGI-078) is an orally active non-toxic small molecule ErbB2 kinase inhibitor. ER121 shows potent antitumor activity can be used for the research of HER2-related breast cancer[1].
CAS Number
2360839-74-1
Product Name Alternative
SGI-078
UNSPSC
12352005
Target
EGFR
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(NC1=CC2=C(NC3=CC=C(C(Cl)=C3)F)N=CN=C2C=C1OCC)/C=C/CN(CCCO)C
Molecular Formula
C24H27ClFN5O3
Molecular Weight
487.95
References & Citations
[1]Goel PN, et al. Targeting erbB Pathways in Breast Cancer: Dual Kinase Inhibition for Brain Metastasis and Prevention of p185HER2/Neu Tumor Development. Breast Cancer (Dove Med Press) . 2024 Oct 30;16:725-733.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ErbB2/HER2

Alternative Products

CatalogName
GTR19274084-01ER121

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