Adavosertib acid

• Description:

  Adavosertib (AZD1775; MK-1775) acid (Compound 9) is a derivative of AZD1775 (HY-10993) and can be used for the synthesis of PROTAC[1].

• Product Name Alternative:

  AZD1775 acid; MK-1775 acid

• UNSPSC:

  12352005

• Target:

  Drug Derivative; Drug Intermediate

• Related Pathways:

  Others

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  O=C(CN1CCN(CC1)C2=CC=C(NC3=NC=C4C(N(CC=C)N(C4=N3)C5=CC=CC(C(C)(C)O)=N5)=O)C=C2)O

• Molecular Formula:

  C28H32N8O4

• Molecular Weight:

  544.60

• References & Citations:

  [1]Zhu S, et al. Design, synthesis, and biological evaluation of Wee1 kinase degraders. Eur J Med Chem. 2022 Dec 5;243:114786.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2714511-66-5]