OZD-MET 01

CAT: 0804-HY-177893Size: 1 EachDry Ice: NoHazardous: No

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CAT#:0804-HY-177893Size:1 Each

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

OZD-MET 01 is a chaperone-med iatedprotein PROTAC-type MET degrader. OZD-MET 01 can inhibit proliferation of H596 and H1437 cells with IC50 values of 3.07 and 3.5 μM. OZD-MET 01 can be used for the research of cancer, such as non-small cell lung cancer[1]. (Structure Note: Pink: MET ligand ; Blue: chaperone ligand (HY-112078) ; MET ligand-Linker: (HY-176950) )

CAS Number

3048497-38-4

UNSPSC

12352005

Target

C-Met/HGFR; PROTACs

Related Pathways

PROTAC; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

C[C@@H](OC1=CC(C2=CN(N=C2)C3CCN(C(OCCOCCNC(C4=CC(CN(C(C5=CC(C(C)C)=C(O)C=C5O)=O)C)=CC=C4)=O)=O)CC3)=CN=C1N)C6=C(Cl)C(F)=CC=C6Cl

Molecular Formula

C45H50Cl2FN7O8

Molecular Weight

906.83

References & Citations

[1]Joo-hoon AHN, et al. Met protein degradation inducing compound. WO2024144088A1. 2025-06-27|[2]Joo-hoon AHN, et al. Met protein degradation inducing compound. WO2024144088A1. 2025-06-27

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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OZD-MET 01

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