GP1 precursor

• Description :

  GP1 precursor has high affinity to GPIIb/IIIa receptors of activated platelets. GP1 precursor can be radiolabeled with [18F] and used as a PET Tracer for visualizing active platelet aggregation at the molecular level. GP1 precursor can be used for the detection of Thrombi[1].

• Target :

  Integrin

• Related Pathways :

  Cytoskeleton

• Field of Research :

  Cardiovascular Disease

• Smiles :

  O=C([C@H]1CN(CCC1)C(CCC2CCN(CC2)C(OC(C)(C)C)=O)=O)N[C@H](C3=CN=CC(OCCOS(=O)(C4=CC=C(C=C4)C)=O)=C3)CC(OC(C)(C)C)=O

• Molecular Formula :

  C40H58N4O10S

• Molecular Weight :

  786.97

• References & Citations :

  [1]Hugenberg V, et al. GMP-Compliant Radiosynthesis of [18F]GP1, a Novel PET Tracer for the Detection of Thrombi. Pharmaceuticals (Basel) . 2021 Jul 28;14 (8) :739.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1423134-36-4]