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Izicopan

CAT: 0804-HY-177094Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-177094Size:1 Each
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Description
Izicopan (INF056) is a complement factor C5a receptor antagonist. Izicopan inhibits C5a-induced calcium mobilization with an IC50 of 10-100 nM[1].
CAS Number
2489430-53-5
Product Name Alternative
INF056
UNSPSC
12352005
Target
Complement System
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=C(C=CC=C1F)F)N2[C@@H](C3=CC=C(C=C3)NC4CCCC4)[C@H](C[C@H](C2)C(F)(F)F)C(NC5=CC(C(F)(F)F)=C(C=C5)C)=O
Molecular Formula
C33H31F8N3O2
Molecular Weight
653.61
References & Citations
[1]Yong Li, et al. Fused piperidinyl bicyclic and related compounds as modulators of c5a receptor. Patent. WO2020182384
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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