ADC-VI

• Description :

  ADC-VI (Compound 6) is a conjugate of a toxic molecule and a linker, in which the cytotoxin carried by CPD6 is Deruxtecan (HY-13631E) . Tricyclene is used to form an antibody-drug conjugate (ADC) by a chemical conjugation reaction through linking with an anti-FGFR2b antibody[1].

• UNSPSC :

  12352211

• Target :

  Drug-Linker Conjugates for ADC

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Field of Research :

  Cancer

• Smiles :

  COCCOCCOCCOCCOC(C=C1COC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=C(C=C1)NC([C@H](C)NC([C@H](C(C)C)NC(CO[C@@H]8O[C@@H]([C@H]([C@@H]([C@H]8O)O)O)C(NCCN9C(C=CC9=O)=O)=O)=O)=O)=O

• Molecular Formula :

  C63H77FN8O22

• Molecular Weight :

  1317.32

• References & Citations :

  [1]Panjiajia, et al. Resistance FGFR2b antibodies and antibody-drug conjugates. CN120424212 A.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3031725-06-8]