TLCD1-IN-1

• Description :

  TLCD1-IN-1 (compound MB-4A) is a covalent TLCD1 inhibitor. TLCD1-IN-1 stereoselectively engages and inhibits TLCD1 in HepG2 cells[1].

• UNSPSC :

  12352005

• Target :

  Endogenous Metabolite

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Metabolic Disease

• Smiles :

  O=C(N1[C@H](COP2(SCCO2)=S)[C@@H](C3=CC=C(Cl)C=C3)C1)C4=CC=C(OCO5)C5=C4

• Molecular Formula :

  C20H19ClNO5PS2

• Molecular Weight :

  483.93

• References & Citations :

  [1]Sharma HA, et al. Proteomic Ligandability Maps of Phosphorus (V) Stereoprobes Identify Covalent TLCD1 Inhibitors. bioRxiv [Preprint]. 2025 Jan 31:2025.01.31.635883.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported