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BBOX-IN-1

CAT: 0804-HY-176418Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-176418Size:1 Each
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Description
BBOX-IN-1 (compound 58) is a potent BBOX inhibitor with an IC50 of 0.02 μM. BBOX-IN-1 can be used in the study of triple negative breast cancer (TNBC) [1].
CAS Number
3106496-37-8
UNSPSC
12352005
Target
Mitochondrial Metabolism
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(N1OCC2=CSC=N2)C(C(NC(C)(C)C(O)=O)=O)=C(O)C3=C1C=CC=C3
Molecular Formula
C18H17N3O6S
Molecular Weight
403.41
References & Citations
[1]Corner TP, et al. Derivatives of the Clinically Used HIF Prolyl Hydroxylase Inhibitor Desidustat Are Efficient Inhibitors of Human γ-Butyrobetaine Hydroxylase. J Med Chem. 2025 May 8;68 (9) :9777-9798.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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GTR19257805-01BBOX-IN-1
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480877FBXL15 (F-bBox/LRR-Repeat Protein 15)
209722-01BBOX1 (Gamma-butyrobetaine Hydroxylase, BBH, BBOX, G-BBH, Gamma-BBH) discontinued
MBS6408207-01BBOX1 (Gamma-butyrobetaine Hydroxylase, BBH, BBOX, G-BBH, Gamma-BBH) (HRP)
MBS6408205-01BBOX1 (Gamma-butyrobetaine Hydroxylase, BBH, BBOX, G-BBH, Gamma-BBH) (Biotin)
MBS6408203-01BBOX1 (Gamma-butyrobetaine Hydroxylase, BBH, BBOX, G-BBH, Gamma-BBH) (AP)
MBS6408206-01BBOX1 (Gamma-butyrobetaine Hydroxylase, BBH, BBOX, G-BBH, Gamma-BBH) (FITC)
MBS6408204-01BBOX1 (Gamma-butyrobetaine Hydroxylase, BBH, BBOX, G-BBH, Gamma-BBH) (APC)
MBS6408213-01BBOX1 (Gamma-butyrobetaine Hydroxylase, BBH, BBOX, G-BBH, Gamma-BBH) (PE)

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