AVI-4206

• Description :

  AVI-4206 is a selective Mac1 inhibitor with an lC50 of 64 nM. AVI-4206 reduces viral replication, restores an interferon response, and leads to a survival benefit in an animal model of SARS-CoV-2 infection. AVI-4206 can be used the study of SARS-CoV-2 infection[1].

• UNSPSC :

  12352005

• Target :

  SARS-CoV

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Smiles :

  O=C(NCC)NC1=CC=CC2=C1NC3=NC=NC(NN4C(C)(C)CCC4=O)=C32

• Molecular Formula :

  C19H23N7O2

• Molecular Weight :

  381.43

• References & Citations :

  [1]Suryawanshi RK, et al. The Mac1 ADP-ribosylhydrolase is a Therapeutic Target for SARS-CoV-2. bioRxiv [Preprint]. 2024 Aug 29:2024.08.08.606661.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [3105041-48-0]