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Rac1-IN-5

CAT: 0804-HY-175341-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-175341-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Rac1-IN-5 is a specific, reversible inhibitor of RAC1 (KD = 30 nM) . Rac1-IN-5 competes with guanine nucleotides for specific binding to RAC proteins, effectively blocking RAC1 activity and RAC1-dependent cellular functions. Rac1-IN-5 exhibits anti-tumor metastasis effects in vivo and can improve survival. Rac1-IN-5 can be used to study invasive cancers such as triple-negative breast cancer and colon cancer[1].
CAS Number
694515-65-6
UNSPSC
12352100
Target
Acyltransferase; Akt; Ras
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; Metabolic Enzyme/Protease; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
99.84
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC=C(C=C1)SCCC(NC2=CC=C(C=C2)S(NC3=CC(OC)=CC=C3OC)(=O)=O)=O
Molecular Formula
C24H26N2O5S2
Molecular Weight
486.60
References & Citations
[1]Dilasser F, et al. A Rac-specific competitive inhibitor of guanine nucleotide binding reduces metastasis in triple-negative breast cancer. Cell Rep Med. 2025 Jul 15;6 (7) :102233.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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