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SufS-IN-1

CAT: 0804-HY-175181Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-175181Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SufS-IN-1, a (2R,3R) -3-ethoxycarbonylaziridine-2-carboxylic acid (EAC), is a selective Cysteine desulfurase type II (SufS) inhibitor. SufS-IN-1 significantly inhibits the SufS activity by covalently binding to the cofactor PLP to form a stable PLP-ligand conjugates. SufS-IN-1 can be used for pathogenic microorganisms research, such as Plasmodium falciparum, Staphylococcus aureus and Mycobacterium tuberculosis[1].
CAS Number
167933-78-0
UNSPSC
12352211
Target
Bacterial; Parasite
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C([C@]1([H])N[C@@]1([H])C(OCC)=O)O
Molecular Formula
C6H9NO4
Molecular Weight
159.14
References & Citations
[1]Fujishiro T, et al. Discovery of an Aziridine-Based Inhibitor That Targets Cysteine Desulfurase Type II SufS via High-Throughput X-ray Crystallography[J]. ACS Medicinal Chemistry Letters, 2025.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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