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Dioxopiperidin-phthalimidine-PEG3-NBoc

CAT: 0804-HY-174879Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-174879Size:1 Each
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Description
Dioxopiperidin-phthalimidine-PEG3-NBoc is a conjugate of the CRBN ligand and the linker (E3 Ligase Ligand-Linker Conjugate). Dioxopiperidin-phthalimidine-PEG3-NBoc can be used for synthesizing Bcl-xL PROTAC degrader PZ671 (HY-174876).
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C1N(C(CC2)C(NC2=O)=O)CC3=C1C=CC(CCCOCCOCCOCCN(C)C(OC(C)(C)C)=O)=C3
Molecular Formula
C28H41N3O8
Molecular Weight
547.64
References & Citations
[1]Zhang P, et al. Discovery of PZ671, a highly potent and in vivo active CRBN-recruiting Bcl-xL degrader. RSC Med Chem. 2025 May 23.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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